Artikel mit Reviewverfahren:


GRUNEWALDT-STÖCKER, G., MAHNKOPP, F., POPP, C., MAISS, E. AND T. WINKELMANN (2019): Diagnosis of apple replant disease (ARD): Microscopic evidence of early symptoms in fine roots of different apple rootstock genotypes. Scientia Horticulturae 243: 583-594.


KANFRA, X., LIU, B., BEERHUES, L., SØRENSEN, S. AND HEUER, H. (2018): Free-Living Nematodes Together With Associated Microbes Play an Essential Role in Apple Replant Disease. Front. Plant Sci. 9:1666. (zum Downloadbereich)


LUCAS, M., BALBIN-SUAREZ, A., SMALLA, K. AND D. VETTERLEIN (2018): Root growth, function and rhizosphere microbiome analyses show local rather than systemic effects in apple plant response to

replant disease soil. PLoS ONE 13: e0204922. (zum Downloadbereich)

MAHNKOPP, F., SIMON, M., PÄTZOLD, S., LEHNDORFF, E., WREDE, A. AND T. WINKELMANN (2018): Induction and diagnosis of apple replant disease (ARD) a matter of heterogenous soil properties? Scientia Horticulturae 241: 167-177.


WINKELMANN, T., SMALLA, K., AMELUNG, W., BAAB, G., GRUNEWALDT-STÖCKER, G., KANFRA, X., MEYHÖFER, R., REIM, S., SCHMITZ, M., VETTERLEIN, D., WREDE, A., ZÜHLKE, S., GRUNEWALDT, J., WEIß, S. AND M. SCHLOTER (2019): Apple Replant Disease: Causes and Mitigation Strategies. Curr. Iss. Mol. Biol. 30: 89-106. (zum Downloadbereich)

REIM, S., SIEWERT, C., WINKELMANN, T., WÖHNER, T., HANKE, M.-V. AND FLACHOWSKY, H. (2019). Evaluation of Malus genetic resources for tolerance to apple replant disease (ARD). Scientia Horticulturae, 108517.

GAO W, SCHLÜTER S, BLASER SRGA, SHEN J AND VETTERLEIN D (2019): A shape-based method for automatic and rapid segmentation of roots in soil from X-ray computed tomography images: Rootine. Plant and Soil, 441, 643–655 (2019)

POPP, C., GRUNEWALDT-STÖCKER, G. AND MAISS, E. (2019): A soil-free method for assessing pathogenicity of fungal isolates from apple roots. J Plant Dis Prot (2019) 126: 329.

CAVAEL, U., DIEHL, K. AND LENTZSCH, P. (2019): Assessment of growth suppression in apple production with replant soils. Ecological Indicators, Vol. 109, February 2020.

RADL, V., WINKLER, J.B., KUBLIK, S., YANG, L., WINKELMANN, T., VESTERGAARD, G., SCHRÖDER, P. AND SCHLOTER, M. (2019): Reduced microbial potential for the degradation of phenolic compounds in the rhizosphere of apples seedlings grown in soils affected by replant disease. Environmental Microbiome 14, 8 (2019) 

SIMON, M., LEHNDORFF, E., WREDE, A. AND AMELUNG W. (2020): In-field heterogeneity of apple replant disease: Relations to abiotic soil properties. Scientia Horticulturae, Vol. 259.

REIM, S., ROHR, A., WINKELMANN, T., WEISS, S., LIU, B., BEERHUES, L., SCHMITZ, M., HANKE, M., FLACHOWSKY, H. (2020): Genes Involved in Stress Response and Especially in Phytoalexin Biosynthesis Are Upregulated in Four Malus Genotypes in Response to Apple Replant Disease. Front. Plant Vol. 10. Sci.


DIEHL, K., CAVAEL, U., SCHWÄRZEL, H. AND LENTZSCH, P. (2020): Orchard floor management strategy to maintain performance of apple trees in replant soils. Acta Hortic. 1270. ISHS 2020.


CAVAEL, U., DIEHL, K. AND LENTZSCH P. (2020): Impact assessment of apple replant disease (ARD) by indication at single tree level in orchards. Acta Hortic. 1270, 281-294.

POPP, C., WAMHOFF, D., WINKELMANN, T.,  MAISS, E. AND G. GRUNEWALDT-STÖCKER Molecular identification of Nectriaceae in infections of apple replant disease affected roots collected by Harris Uni-Core punching or laser microdissection. J Plant Dis Prot 127, 571–582 (2020).

BALBÍN-SUÁREZ, A., LUCAS, M., VETTERLEIN, D., SØRENSEN, S., WINKELMANN, T., SMALLA, K. AND JACQUIOD, S. (2020): Exploring microbial determinants of apple replant disease (ARD): A microhabitat approach under split-root design. FEMS Microbiology Ecology, fiaa211

GRUNEWALDT-STÖCKER, G., POPP, C., WAMHOFF, D., MAISS, E., WINKELMANN, T. (2021): Microscopic evidence of Nectriaceae and other microbes in infected fine root tissue of replant diseased apple plants. Europ J. Hort. Sci. 86(1), 29-40.

CAVAEL, U.; TOST, P.; DIEHL, K.; BÜKS, F.; LENTZSCH, P. (2020): Correlations of Soil Fungi, Soil Structure and Tree Vigour on an Apple Orchard with Replant Soil. Soil Syst. 2020, 4, 70.

MAHNKOPP-DIRKS, F., RADL, V, KUBLIK, S., GSCHWENDTNER, S., SCHLOTER, M. AND WINKELMANN, T. (2021): Molecular barcoding reveals the genus Streptomyces as associated root endophytes of apple (Malus domestica) plants grown in soils affected by apple replant disease. Phytobiomes Journal 2021 5:2, 177-189


ARMIN, R., ZÜHLKE, S., MAHNKOPP-DIRKS, F., WINKELMANN, T.  AND S. KUSARI (2021): Evaluation of Apple Root-associated Endophytic Streptomyces pulveraceus Strain ES16 by an OSMAC-Assisted Metabolomics Approach, Front. Sust. Food Syst. 5:643225

BALBÍN-SUÁREZ, A., JACQUIOD, S., ROHR, A.D., LIU, B., FLACHOWSKY, H., WINKELMANN, T., BEERHUES, L., NESME, J., SØRENSEN, S.J., VETTERLEIN, D., AND K. SMALLA (2021): Root exposure to apple replant disease soil triggers local defense response and rhizoplane microbiota dysbiosis. FEMS Microbiol. Ecol. 2021; Volume 97, Issue 4, April 2021. fiab031

ARMIN, R., ZÜHLKE, S., GRUNEWALDT-STÖCKER, G., MAHNKOPP-DIRKS, F., AND KUSARI, S. (2021): Production of Siderophores by an Apple Root-Associated Streptomyces ciscaucasicus Strain GS2 Using Chemical and Biological OSMAC Approaches. Molecules 2021, 26, 3517.

REIM, S., CESTARO, A., SIEWERT, C., WÖHNER, T., MAHNKOPP-DIRKS, F., WINKELMANN, T., HANKE, M.-V. AND FLACHOWSKY, H. (2021): Evaluation of tolerance to apple replant disease (ARD) in Malus germplasm. Acta Hortic. 1307, 327-334

ROHR, A.-D., SCHIMMEL, J., LIU, B., BEERHUES, L., GUGGENBERGER, G., AND T. WINKELMANN (2020): Identification and validation of early genetic biomarkers for apple replant disease. PLoS ONE 15(9): e0238876.

ROHR, A.-D., STAUDT, J., CZIBORRA, K., FRITZ, A., SCHMITZ, M. AND T. WINKELMANN (2021): Split-root approach reveals localized root responses towards apple replant disease (ARD) in terms of ARD biomarker gene expression and content of phenolic compounds. Scientia Horticulturae, Volume 286,

2021, 110117,

BENNING, S., BRUGNONE, N., SIANI, R., KUBLIK, S., SCHLOTER, M., & RADl, V. (2021). Complete Genome Sequences of Two Rhodococcus sp. Strains with Large and Linear Chromosomes, Isolated from Apple Rhizosphere. Microbiology resource announcements, 10(24), e0015921.

BUSNENA, B. A., BEUERLE, T., MAHNKOPP-DIRKS, F., WINKELMANN, T., BEERHUES, L., AND LIU, B. (2021). Formation and exudation of biphenyl and dibenzofuran phytoalexins by roots of the apple rootstock M26 grown in apple replant disease soil. Phytochemistry, 192, 112972. Advance online publication.

KANFRA, X., WREDE, A., MAHNKOPP-DIRKS, F., WINKELMANN, T., HEUER, H., (2022): Networks of free-living nematodes and co-extracted fungi, associated with symptoms of apple replant disease. Applied Soil Ecology. 172, 104368.



KANFRA X., WREDE A., MOLL J., HEUER H. (2022). Nematode–Microbe Complexes in Soils Replanted with Apple. Microorganisms. 2022; 10(1):157.

MAHNKOPP-DIRKS F, RADL V, KUBLIK S, GSCHWENDTNER S, SCHLOTER M AND WINKELMANN, T. (2022): Dynamics of Bacterial Root Endophytes of Malus domestica Plants Grown in Field Soils Affected by Apple Replant Disease. Front. Microbiol. 13:841558.

REIM, S., WINKELMANN, T., CESTARO, A., ROHR, A. D., AND FLACHOWSKY, H. (2022). Identification of Candidate Genes Associated With Tolerance to Apple Replant Disease by Genome-Wide Transcriptome Analysis. Frontiers in microbiology, 13, 888908.

PIELHOP, T.P., POPP, C., KNIERIM, D., MARGARIA, P., AND MAISS, E. (2022): Three new mycoviruses, identified in the apple replant disease (ARD)-associated fungus Rugonectria rugulosa. In Virus Genes.

PIELHOP, T. P., POPP, C., KNIERIM, D., MARGARIA, P., AND MAISS, E. (2022). First report of a chrysovirus infecting a member of the fungal genus Ilyonectria.Archives of virology, 10.1007/s00705-022-05551-2. Advance online publication.

WINKELMANN, T. AND MAHNKOPP-DIRKS, F. (2023): Apple replant disease – new insights into an old problem. Acta Hortic. 1366, 369-376.



MAHMOUD, F. M., KUSARI, S., KUBLIK, S., BENNING, S., SIANI, R., ZÜHLKE, S., RADL, V., MAHNKOPP-DIRKS, F., AND SCHLOTER, M. (2023): Draft Genome Sequence of the Bacterial Endophyte Priestia megaterium B1, Isolated from Roots of Apple (Malus domestica). Microbiology resource announcements, e0117222. Advance online publication.

BUSNENA, B. A., BEERHUES, L., LIU, B. (2023). Biphenyls and dibenzofurans of the rosaceous subtribe Malinae and their role as phytoalexins. Planta, 258(4), 78.


Artikel ohne Reviewverfahren:

FLACHOWSKY, H. AND WINKELMANN, TRAUD (2021): Bodenmüdigkeit im Fokus: Die Reaktionen von Apfelpflanzen verstehen, um tolerante Unterlagen zu identifizieren. Obstbau. 46 (5), 267-272.

BAAB G., NACHTWEY C., SCHOENEBECK L., LANKES C. (2019): Mit Senfmehl gegen die Bodenmüdigkeit, in European fruit Magazin (EfM), April, S. 14–17


T. WINKELMANN (2020): Der Apfelnachbaukrankheit auf der Spur – mit Biotest.
Deutsche Baumschule 06/2020: 36-39

MAHNKOPP-DIRKS, F., WINKELMANN, T. (2022): Welche Rolle spielen Bakterien der Gattung Streptomyces in der Nachbaukrankheit bei Apfel? Versuchsberichte Baumschule und Obstbau Jahrgang 2021; S. 26 - 31



ROHR, A.D., WINKELMANN, T. (2021): Frühe Indikatoren für die Nachbaukrankheit bei Apfel. Versuchsberichte Baumschule und Obstbau Jahrgang 2021; S. 21 - 25

FLACHOWSKY, H., MAHNKOPP-DIRKS, F., HARDEWEG, B. UND WINKELMANN, T. (2022): Bodenmüdigkeit überwinden - Mit einem Integrierten Ansatz auf der Suche nach Lösungen. Besseres Obst. 06|22.

WREDE, A., HARDEWEG, B., WINKELMANN, T., STROLKA, B. (2023): Serie Teil 1 - ORDIAmur: Maßnahmen gegen Bodenmüdigkeit beim Apfel geprüft. Deutsche Baumschule 04/2023


WREDE, A., LEHNDORFF, E., BAAB, G., GUGGENBERGER, G., SIMON, M., MEYER, N., PÄTZOLD, S., AMELUNG, W., BOY, J., SCHIMMEL, J., KRÜGER, J., VETTERLEIN, D., WINKELMANN, T (2023): Serie Teil 2 - ORDIAmur: Historie und Beobachtungen zur Bodenqualität. Deutsche Baumschule 05/2023


WREDE, A., WINKELMANN, T., ORTH, N., REIM, S., FLACHOWSKY, H., BAAB, G., SIEFEN, N., SCHMITZ, M., KLOPHAUS, L. (2023): Serie Teil 3 - ORDIAmur: Bewertung von Apfelunterlagen hinsichtlich ihrer Toleranz gegenüber der Nachbaukrankheit. Deutsche Baumschule 06/2023

WREDE. A., BUSNENA, B., SCHRÖPFER, S., BAADER, L., ROHR, A.D., GRUNEWALDT-STÖCKER, G., WINKELMANN, T., LIU, B., BEERHUES, L. (2023): Serie Teil 4 - ORDIAmur: Reaktion von Apfelpflanzen auf die Bodenmüdigkeit. Deutsche Baumschule 07/2023.

WREDE, A., MAHNKOPP-DIRKS, F., SCHLOTER, M., BENNING, S., HAUSCHILD, K., SMALLA, K., ORTH, N., BALBÍN-SUÁREZ, A., PIELHOP, T., POPP, C., GRUNEWALDT-STÖCKER, G., MAISS, E., WINKELMANN, T. (2023): Serie Teil 5 - ORDIAmur: Effekte von Apfelanbau auf Bodenmikroorganismen und Wurzelendophyten. Deutsche Baumschule 08/2023.

WREDE, A. KANFRA, X.HEUER, H., LIU, B., BEERHUES, L. (2023): Serie Teil 6 - ORDIAmur Die Rolle von Nematoden und Mikroorganismen bei der Nachbaukrankheit von Apfel. Deutsche Baumschule 09/2023.


POPP, GÖSTA CAROLIN DORETTE: Investigations on the occurrence of fungal root endophytes and an associated mycovirus in context with apple replant disease. Hannover : Gottfried Wilhelm Leibniz Universität, Diss., 2020, VII, 75 S. DOI:

MAHNKOPP-DIRKS, FELIX: Bacterial endophytes in apple (Malus domestica) rootstocks grown in apple replant disease affected and non-affected soils. Hannover : Gottfried Wilhelm Leibniz Universität, Diss., 2021, iii, 132 S. DOI: